Premature infants and neutropenic cancer patients Skin and soft tissue infections Hemorrhage and necrosis People with burns or wound infections It is the most common cause of infections of burn injuries and of the outer ear otitis externaand is the most frequent colonizer of medical devices e. Pseudomonas can be spread by equipment that gets contaminated and is not properly cleaned or on the hands of healthcare workers.
In cold climate regions, surface soil layers experience repeated temperature fluctuations around the freezing point known as freeze-thaw FT cycles. With global climate change, annual soil FT cycles have increased, and this trend is expected to continue.
It is therefore of interest to understand how FT cycles impact soil microbial communities. This study investigates the influence of FT cycles on the growth, culturability, biofilm formation, and virulence of the bacterial opportunistic pathogen Pseudomonas aeruginosa, a ubiquitous bacterium found in soil and water, responsible for infections in immunocompromised hosts.
Our findings demonstrate that exposure to FT had no significant effect on growth or culturability of the bacteria. However, FT treatment significantly increased biofilm formation and delayed the onset of swimming motility, factors that are important for the pathogenicity of P.
An in vivo study using a chronic infection model revealed an increase in the virulence of P. These results suggest that the impact of climate change on natural FT cycles may be affecting the ecology of soil-borne pathogens and host-pathogen interactions in unexpected ways.
Read this article multiple options.Some superbug strains of Pseudomonas aeruginosa cause infections that are resistant to nearly all types of antibiotics.
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Mediators of Inflammation is a peer-reviewed, Open Access journal that publishes original research and review articles on all types of inflammatory mediators, including cytokines, histamine, bradykinin, prostaglandins, leukotrienes, PAF, biological response modifiers and the family of cell adhesion-promoting molecules.
Tolerance of Pseudomonas pseudoalcaligenes KF to metals, polychlorobiphenyls and chlorobenzoates: effects on chemotaxis-, biofilm- and planktonic-grown cells Valentina Tremaroli Department of Biology, General Microbiology Unit, University of Bologna, Bologna, Italy. The purpose of this study was to determine whether short-term exposure to clinically relevant concentrations of Pseudomonas aeruginosa lipopolysaccharide (LPS) impairs vasoreactivity of resistance arterioles in the intact spinotrapezius muscle microcirculation and, if so, to determine the mechanisms mediating this response.
Pseudomonas aeruginosa and Pseudomonas cepacia are both opportunistic pathogens of patients with cystic fibrosis. The binding characteristics of these two species were compared to determine if they use similar mechanisms to adhere to respiratory epithelial cells.